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The Institut de Génomique Fonctionnelle (IGF) is a multidisciplinary research center. The IGF's main activity is devoted to fundamental research using functional genomics to explore normal and pathological cell signaling and communication processes in various fields, particularly neurobiology, cardiology, endocrinology and oncology. Main activities range from structural pharmacology to systems biology, from the development of preclinical models of disease to translational research, to study a variety of pathologies, including neurological and psychiatric diseases, cardiac dysfunction, diabetes and cancer. One of IGF's main objectives is to identify new concepts in molecular medicine and evaluate new strategies for the development of diagnostic and therapeutic tools. Label: Unité Mixte de Research (UMR)Tutelles principales: CNRS, UM, InsermResearch cluster: Health BiologyPhD school: Chemical and Biological Sciences for HealthHAL portal: publications of the structure WEBSITE

The Institut Desbrest d'Épidémiologie et de Santé Publique (IDESP) aims to understand the development and evolution of chronic diseases, which affect over 30% of the population and absorb 80% of healthcare expenditure. To achieve this, the INSERM-University of Montpellier Joint Research Unit is using a new approach that takes account of the environment in the broadest sense, and of care trajectories through multimodal markers (clinical, biological, behavioral, psychological, social, environmental), drawing on the power of mathematics dedicated to massive data. The aim is to design optimized care and prevention pathways for relevant patient targets. Allergic and respiratory diseases, diabetes, obesity, kidney disease, vascular disease, inflammatory rheumatism and cancer are the focus of initial modeling. Label: Unité Mixte de Research (UMR)Tutelles principales: UM, InsermResearch cluster: Biology and HealthPhD schools: Information, Structures, Systems; Chemical and Biological Sciences for HealthHAL portal: publications of the structure SITE WEB - Page HAL

GENOPOLYS can be used for meetings, conferences and workshops in the fields of biology and health, thanks to its meeting rooms, amphitheatre and two practical rooms. GENOPOLYS is a hub of exchange, aimed at: the general public, with the aim of contributing to the citizen's scientific and medical culture, and participating in the dialogue between science and society; researchers and doctors, by promoting the integration of clinical research with fundamental research; industrialists, with the aim of integrating the world of research into business through training, interaction and development. Label: Unité d'Appui et de Research (UAR)Main supervisory bodies: CNRS, UM, InsermResearch cluster: Biology and Health WEBSITE

The "EuroMov Digital Health in Motion" research unit aims to foster the cross-fertilization of artificial intelligence, movement and health sciences to understand human behavioral plasticity in order to improve sensorimotor performance and envisage new therapeutic approaches, and to find in it a scientific metaphor, a source of inspiration for new digital approaches: automatic learning or adaptive control of complex systems, human/machine interaction and context-sensitive software systems. https://youtu.be/xaUOKgoUwYI?list=PL6WmOx60MnJe_iazdaxlxc1zC3Mx1K3Z0 This line of research on "Digital Health in Motion" ultimately aims to gain a better understanding of the etiology of human movement, considered as the level of integration of biological and cognitive phenomena, in the course of our ongoing informational exchanges with the environment. Perception In Action & Synchronization (PIAS): discover the laws governing human perception in moving agents (perception in action) and human-environment synchronization in general. Monitoring and Improving Behaviors (MIB): providing users with advice on how to improve their behaviors to achieve better health, quality of life or sports performance, with a particular focus on software engineering. Learning and Complexity Theme (LAC) focuses on the study of human learning and complexity through health movement signatures, clinical data and neural activity indicators, in particular by developing interpretable models. Semantics and Taxonomy of Movement (SemTaxM): to identify taxonomic classifications of movement and define a theory of semantics carried by movement and semantic models anchored in specific contexts. The transverse Factory axis aims to improve reproducibility of results and accelerate translational research and technology transfer by providing standardized and documented approaches with an open data dissemination strategy. Label: UR_UM102Main supervisors: UM, IMT Mines AlesResearch cluster: Biology and HealthPhD schools: Information, Structures, Systems; Human Movement SciencesHAL portal: publications of the structure WEBSITE

The DMEM laboratory is a joint research unit of INRA and the University of Montpellier. We are interested in understanding the tissue, cellular and molecular mechanisms that enable skeletal muscle to develop correctly and adapt to its environment. Our hypothesis is that abnormalities in muscle tissue adaptation to environmental changes (diet, level of physical activity) can modulate body homeostasis and, more broadly, health status. DMEM is therefore a fundamental research unit whose aim is to advance our knowledge of skeletal muscle function and physiology. We are also open to the possible applications of our research, as demonstrated by our partnerships with private companies interested in our results. Label: Unité Mixte de Research (UMR)Main supervisors: UM, INRAResearch cluster: Biology and HealthPhD schools: Human Movement Sciences; Chemical and Biological Sciences for HealthHAL portal: publications of the structure WEBSITE

Label : Unité Mixte de Research (UMR)Tutelles principales : UM, Inserm, UPS ToulouseResearch pole : Biology and HealthPhD school : Chemical and Biological Sciences for HealthHAL portal : publications of the structure WEBSITE

The Montpellier Cell Biology Research Center is a laboratory of the CNRS and the University of Montpellier. The CRBM is internationally recognized in the field of molecular and cell biology. Its research focuses on understanding the mechanisms controlling cell division, morphology and adhesion under normal and pathological conditions, with particular emphasis on cytoskeleton dynamics, post-translational modifications and intracellular signaling mechanisms regulating these cellular activities. Label: Unité Mixte de Research (UMR)Tutelles principales: CNRS, UMPôle de recherche: Biologie SantéDoctoral school: Sciences Chimiques et Biologiques pour la SantéPortail HAL : publications de la structure WEBSITE

https://youtu.be/U-4QGKRe4wY Le CEMIPAI est un laboratoire de services du CNRS et de l’université de Montpellier, ouvert aux équipes académiques et aux entreprises. Il s’organise autour de l’un des plus grands laboratoires de sécurité microbiologie de niveau L3 de France, permettant de travailler en atmosphère contrôlée sur les prélèvements biologiques infectieux et les agents biologiques de classe 3, comme le virus de l’immunodéficience humaine (VIH), les virus des hépatites ou les virus transmis par les moustiques (Chikungunya, Dengue, Zika), les bactéries pathogènes et les prions. Le CEMIPAI accueille les équipes, forme les chercheurs à la manipulation des agents infectieux et développe des tests en cultures cellulaires permettant de rechercher des molécules d’intérêt thérapeutique développées par les chercheurs du privé et du public. Des équipements de pointe en microscopie super résolue permet d’observer cellules infectées, virus et bactéries à des échelles nanométriques. Label : Unité d’Appui et de Recherche (UAR)Tutelles principales : CNRS, UMPôle de recherche : Biologie SantéPortail HAL : publications de la structure SITE WEB

The overall aim of the CBS is to carry out research at the cutting edge of structural biology, biophysics and bioengineering to identify and characterize the fundamental mechanisms of life and their regulation, at different scales of time and space (from single molecules to living tissues and organisms) and using integrative approaches. We are particularly interested in understanding the molecular and physical determinants of these processes, using state-of-the-art methodologies. We believe that the answer to these objectives involves the study of the structure and dynamics of supramolecular assemblies at different scales, as well as a detailed understanding of their assembly and regulation mechanisms. In addition, our ambition is to study these processes in more integrated contexts such as living cells or model organisms. Where possible, we also exploit this knowledge to design new therapeutic strategies for human health and disease. Label: Unité Mixte de Research (UMR)Main supervisory bodies: CNRS, UM, InsermResearch cluster: Biology and HealthPhD schools: Information, Structures, Systems; Chemical and Biological Sciences for HealthHAL portal: publications of the structure WEBSITE

BioCampus Montpellier is a federative research structure comprising 12 high-level technology platforms. These platforms serve a scientific community of 2,000 Professors , most of whose teams belong to the AGRO, CeMEB and EpiGenMed labexes. The UMS offers its services to players in the research units as well as to industrialists, with the aim of creating new collaborative networks. Its platforms offer "open access" services, scientific and technical expertise, training in the form of technology workshops, etc. Themes: Bioinformatics, Structural Biology, Breeding and Functional Exploration, Histology, Imaging, Small Animal Imaging, Molecular Combining, Recombinant Proteins, Genomics, Pharmacology, Proteomics, Vectorology. Label: Unité d'Appui et de Research (UAR)Tutelles principales: CNRS, UM, InsermResearch cluster: Health BiologyHAL portal: publications of the structure WEBSITE

Our project focuses on biocommunication between the cardiovascular/renal axis and metabolic tissues, in the complex pathophysiological context of metabolic syndrome. Our work aims to better characterize the pathophysiological mechanisms involved in the damage to different target tissues (cardiovascular and metabolic) during metabolic dysfunction, as well as the biocommunication pathways between these tissues. Thanks to this integrative approach to chronic diseases, we hope to develop new therapeutic strategies, with the aim of preventing damage to cardiovascular and metabolic tissues and thus reducing cardiovascular risk and metabolic dysfunction. Label : UR_UM101Main supervisor : UMPôle de recherche : Biologie SantéDoctoral school : Sciences Chimiques et Biologiques pour la SantéHAL portal : publications of the structure WEBSITE

The vocation of the Sciences pour l'Œnologie unit is to develop generic research in plant biology, microbiology, biochemistry, chemistry and physical chemistry, with the wine industry as its main field of application. The unit's researchers focus mainly on topics relating to: Integrative physiology of oenological yeasts and control of alcoholic fermentation; Phenolic compounds (biosynthesis, reactivity, physico-chemical interactions, properties, valorization). Label: Unité Mixte de Research (UMR)Tutelles principales : UM, INRAE, Institut AgroPôle de recherche : Pôle Agriculture-Environnement-Biodiversité (AEB)École doctorale : Biodiversité, Agriculture, Alimentation, Environnement, Terre, EauPortail HAL : publications de la structure SITE WEB

The QualiSud unit develops scientific activities aimed at analyzing, understanding and optimizing the process of building food quality throughout the processing chain. Particular attention is paid to sensory quality, health effects and sanitary risks. UMR QualiSud's research activities are structured around five scientific actions: bioguidance of processes by the sensory and health qualities of foodstuffs; post-harvest quality control of fresh fruit and vegetables; mycotoxin prevention and control strategies throughout the food chain; study of transfers and reaction kinetics during the fermentation of solid foodstuffs; multi-criteria analysis and design for decision support in the agri-food industry. Label: Unité Mixte de Research (UMR)Tutelles principales : UM, CIRAD, IRD, Institut Agro, U RÉUNION, UAPVResearch cluster: Agriculture, Environment, Biodiversity - AEBPhD school: Biodiversity, Agriculture, Food, Environment, Land, WaterHAL portal: publications of the structure WEBSITE

Numerous interactions take place between the various micro- and macro-organisms of agro-ecosystems and plants. These interactions, which determine plant health, growth and productivity, are often poorly understood. UMR PHIM generates knowledge and solutions to improve plant health, productivity and quality. PHIM uses molecular biology and genetics, population genetics and genomics, epidemiology and population dynamics and modeling to study these interactions at scales ranging from the cell to the crop plot. Label: Unité Mixte de Research (UMR)Main supervisors: CIRAD, INRAE, IRD, Institut AgroTutelle secondaire: UMPôle de recherche: Agriculture, Environnement, Biodiversité - AEBDoctoral school: Biodiversity, Agriculture, Food, Environment, Land, WaterHAL portal: publications of the structure WEBSITE

OREME focuses its scientific activities on natural hazards and the impact of global and anthropogenic changes on the Mediterranean area, thanks to the scientific and technical skills of its partners in geosciences, hydrosciences, biodiversity sciences and ecology. Its mission is: to support the development of systematic observation activities in the sciences of the universe and the environment; to support the construction of open, shared, internationally referenced environmental databases; to encourage the pooling of analytical resources (observation, experimentation, modelling) and know-how; to act as a local relay for national observation networks, and to position itself as a key player in environmental actions focused on the Mediterranean. OREME focuses on 3 fundamental issues: the origin and assessment of natural and anthropogenic hazards and disturbances; the recording of recent and current global changes, their links with anthropogenic factors and, in particular, changes in the use of Mediterranean environments; and the response of the systems and mechanisms involved. Relying on the training components of the University of Montpellier for its teaching mission, OREME focuses on its ability to mobilize heavy, long-term observation resources and recognized scientific and technical skills in a wide range of aspects of the Mediterranean physical, chemical and biological environment: geodesy, gravimetry and deformation of the Earth and its surface; hydrogeological, hydric and geophysical monitoring of aquifers, particularly karstic; monitoring of the Languedoc coastline, interface between watershed and marine space, coastline; pollution and biological adaptability downstream of former mining sites; flow measurements (CO2, water, gas) and ecosystem functioning; phenology of terrestrial flora and fauna; dynamics of animal and plant communities; population dynamics of model organisms. It is also home to three major regional technical platforms: GLADYS for integrated coastal studies, AETE for water pollution analysis, and the Station Marine de Sète (SMEL). OREME's permanent observation facilities enable data on environmental change to be collected and disseminated nationally and internationally, as well as enabling fundamental and applied research to be carried out. Label : Unité d'Appui et de Research (UAR)Tutelles principales : CNRS, UM, INRAE, IRDPôle de recherche : Agriculture, Environnement, Biodiversité - AEBPortail HAL : publications de la structure SITE WEB

MIVEGEC develops integrative research on the molecular and ecological mechanisms that maintain and/or amplify the maintenance and transmission of pathogenic agents. The research topics cover a broad spectrum, combining fundamental aspects of biology, genetics, ecology and evolution of parasitic and symbiotic systems, with the more specific objectives of developing tools and strategies to reduce the spread of disease in humans and animals, notably through integrated ecosystem management and insect vector control. This places MIVEGEC at the interface between Public Health and the Environment, Biology and Medicine, Ecology and Evolution. This research applies to various infectious models (parasites, viruses, bacteria, etc.) as well as to non-infectious models such as cancer. Label: Unité Mixte de Research (UMR)Primary supervisors: CNRS, UM, IRDSecondary supervisors: INRAResearch cluster: Agriculture, Environment, Biodiversity - AEBPhD schools: Chemical and Biological Sciences for Health; Biodiversity, Agriculture, Food, Environment, Land, WaterHAL portal: publications of the structure WEBSITE